Opportunity Information: Apply for 21 503

The National Science Foundation (NSF) grant opportunity titled Sustaining Infrastructure for Biological Research (often referred to as the "Sustaining" Program) is designed to keep important, already-established research infrastructure running and accessible to the broader biology research community. Rather than funding the creation of brand-new platforms or early-stage experimental resources, this program focuses on maintaining mature, proven infrastructure that researchers actively rely on to produce scientific results. The infrastructure supported must advance contemporary biology and align with research areas supported by NSF's Directorate for Biological Sciences (BIO), meaning it can span a wide range of biological disciplines as long as it serves the BIO community and its collaborators.

A central theme of the opportunity is continuity and broad utility. The program emphasizes sustaining critical resources that function as shared infrastructure, especially in two major categories: cyberinfrastructure (such as data resources, software platforms, computational tools, databases, and related digital systems that enable biological research) and biological living stocks (such as living collections or resources that must be maintained over time to remain valuable, including organisms or other biological materials that are kept viable and distributed for research use). NSF's goal is to ensure these resources remain available and dependable for a wide user base, not limited to a single lab or a narrow research niche. In practical terms, proposals are expected to show that the resource is already in operation, is widely used (or demonstrably positioned to serve a broad community), and is essential to enabling strong scientific outcomes for many users.

This funding opportunity is a discretionary grant program administered by NSF under the Science and Technology and other Research and Development category (CFDA/Assistance Listing 47.074). Proposals can be submitted at any time (there is no fixed deadline listed), which makes it more flexible than many government funding programs that rely on annual cycles. NSF anticipates making about three awards under this opportunity, and the listed award ceiling is shown as 0, which usually indicates the ceiling is not specified in the summary and applicants should consult the full solicitation or program guidance to understand typical award sizes, project scopes, and budget expectations. Eligibility is described broadly as "Others (see text field entitled Additional Information on Eligibility for clarification)," signaling that eligibility may extend beyond the most common categories but requires checking the detailed eligibility language in the full announcement.

Overall, this opportunity is best understood as NSF's mechanism for keeping key biological research infrastructure stable, maintained, and accessible so that researchers across many institutions and subfields can continue to generate high-impact science. The program prioritizes resources that are already mature and widely applicable, and it expects funded projects to focus on reliable operation, continued availability, and demonstrated value to a broad community of users supported by BIO and collaborating organizations.

  • The National Science Foundation in the science and technology and other research and development sector is offering a public funding opportunity titled "Sustaining Infrastructure for Biological Research" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 47.074.
  • This funding opportunity was created on Oct 03, 2020.
  • Applicants must submit their applications by Proposals accepted anytime. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for 21 503

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