Opportunity Information: Apply for W81XWH 22 VRP TRA
The DoD Vision, Translational Research Award (FY22 VRP TRA) is a Department of Defense funding opportunity focused on pushing vision-related research beyond early discovery and into real-world clinical use. The central aim is to support translational projects that take promising findings and actively move them toward practical applications that can prevent, diagnose, lessen, or treat eye injuries and visual dysfunction linked to military exposures. In other words, this program is not meant for purely exploratory or basic science work; it is designed for teams that already have a credible discovery or prototype and can show a realistic, step-by-step plan for turning it into something clinicians can ultimately use.
A strong application under this award is expected to lay out a clear pathway to deliverables such as new drugs, medical devices, or clinical practice guidelines that are mature enough to be ready for definitive testing in clinical trials. The program emphasizes readiness and forward momentum, meaning the proposed work should include tangible milestones that bridge the gap between laboratory success and clinical evaluation. If the project involves developing a drug or device, the program anticipates that regulatory progress will be made during the performance period, with an expectation that an Investigational New Drug (IND) application or an Investigational Device Exemption (IDE) submission will be filed during the project or by the end of the award period when applicable. This makes regulatory planning and documentation a major part of what the DoD expects to see, not an afterthought.
Because navigating FDA requirements can determine whether a translational project succeeds or stalls, the opportunity specifically calls for drug or device development teams to include at least one collaborator who has expertise in the FDA regulatory approval process. This requirement signals that reviewers will likely scrutinize the feasibility of the regulatory strategy, including how the team will handle preclinical evidence, safety considerations, manufacturing or quality systems where relevant, and the design choices needed to support later-stage clinical trials.
Administratively, this opportunity is listed as discretionary and can be funded through a grant or a cooperative agreement, under the Department of Defense (Department of the Army, USAMRAA). It is categorized under science and technology and other research and development, with CFDA number 12.420. Eligibility is described as unrestricted, meaning a wide range of entity types may apply, subject to any additional eligibility notes in the full announcement. The funding opportunity number is W81XWH 22 VRP TRA. The posting dates in the source information indicate it was created on May 10, 2022, with an original closing date of November 9, 2022. The listing notes an expected number of awards of 1, and the award ceiling is shown as 0, which typically indicates that the ceiling is not specified in the summary field and would need to be confirmed in the full funding announcement or related program documents.
Overall, the DoD Vision Translational Research Award is best understood as a late-preclinical to preclinical-to-clinic bridge mechanism for vision research tied to military-relevant exposures, prioritizing projects with a credible development plan, measurable translational milestones, and a defined regulatory path that positions the product or guideline for clinical trial readiness.Apply for W81XWH 22 VRP TRA
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Vision, Translational Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on May 10, 2022.
- Applicants must submit their applications by Nov 09, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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FAQs: DoD Vision, Translational Research Award (FY22 VRP TRA)
What is the DoD Vision, Translational Research Award (FY22 VRP TRA)?
The FY22 VRP TRA is a Department of Defense funding opportunity intended to move vision-related research beyond early discovery and toward real-world clinical use. It focuses on translational work that advances a credible finding or prototype into something that clinicians can ultimately use.
What is the main goal of this award?
The central goal is to support projects that can prevent, diagnose, lessen, or treat eye injuries and visual dysfunction tied to military exposures by actively advancing promising research toward practical clinical applications.
Is this funding intended for basic science or exploratory research?
No. The opportunity is described as not meant for purely exploratory or basic science work. It is designed for teams that already have a credible discovery or prototype and can present a realistic, step-by-step plan to translate it toward clinical use.
What types of deliverables does the program expect?
A strong application is expected to define a clear pathway to deliverables such as new drugs, medical devices, or clinical practice guidelines that are sufficiently mature to be ready for definitive testing in clinical trials.
What does "translational" mean in the context of this opportunity?
In this context, translational means bridging the gap between laboratory success and clinical evaluation by laying out tangible milestones and demonstrating forward momentum toward clinical trial readiness.
What stage of research is this award best suited for?
Based on the description, it is best understood as a late-preclinical to preclinical-to-clinic bridge mechanism for vision research, emphasizing readiness to move into clinical testing.
What are reviewers likely to look for in a strong application?
The description emphasizes a credible development plan, measurable translational milestones, and a defined regulatory path that positions a product or guideline for clinical trial readiness.
Are regulatory milestones expected for drug or device projects?
Yes. For projects developing a drug or device, the program anticipates regulatory progress during the performance period and expects that an Investigational New Drug (IND) application or an Investigational Device Exemption (IDE) submission will be filed during the project or by the end of the award period when applicable.
What is an IND or IDE in relation to this award?
The opportunity specifically references IND and IDE submissions as regulatory filings that may be expected for drug or device development projects, indicating that regulatory planning is a central part of the translational pathway described.
Is FDA regulatory expertise required on the project team?
For drug or device development teams, the opportunity calls for including at least one collaborator with expertise in the FDA regulatory approval process.
Why does the opportunity emphasize FDA regulatory expertise?
The description notes that navigating FDA requirements can determine whether a translational project succeeds or stalls, and signals that reviewers may scrutinize the feasibility of the regulatory strategy.
What aspects of the regulatory strategy may be scrutinized?
The description highlights that reviewers may evaluate how the team will handle topics such as preclinical evidence, safety considerations, manufacturing or quality systems where relevant, and design choices needed to support later-stage clinical trials.
What agency is associated with this funding opportunity?
The opportunity is under the Department of Defense, specifically the Department of the Army, USAMRAA (as listed in the summary information).
What funding mechanisms may be used for awards?
The listing indicates it is discretionary and may be funded through a grant or a cooperative agreement.
What is the CFDA number for this opportunity?
The CFDA number provided is 12.420.
What is the funding opportunity number?
The funding opportunity number is W81XWH 22 VRP TRA.
Who is eligible to apply?
Eligibility is described as unrestricted in the summary, meaning a wide range of entity types may apply, subject to any additional eligibility notes in the full announcement.
How many awards are expected?
The listing notes an expected number of awards of 1.
Is there a maximum award amount (award ceiling)?
The award ceiling is shown as 0 in the summary field. This typically indicates the ceiling is not specified in that summary and would need to be confirmed in the full funding announcement or related program documents.
When was the opportunity posted and when did it close?
The source information indicates it was created on May 10, 2022, and had an original closing date of November 9, 2022.
What research focus area does the program fall under?
It is categorized under science and technology and other research and development, with an emphasis on vision-related translational research connected to military-relevant exposures.
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| DoD Vision, Clinical Trial Award Apply for W81XWH 22 VRP CTA Funding Number: W81XWH 22 VRP CTA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Vision, Focused Translational Team Science Award Apply for W81XWH 22 VRP FTTSA Funding Number: W81XWH 22 VRP FTTSA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Vision, Investigator- Initiated Research Award Apply for W81XWH 22 VRP IIRA Funding Number: W81XWH 22 VRP IIRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DoD Hearing Restoration Focused Research Award Apply for W81XWH 22 HRRP FRA Funding Number: W81XWH 22 HRRP FRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Lupus, Impact Award Apply for W81XWH 22 LRP IPA Funding Number: W81XWH 22 LRP IPA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Lupus, Idea Award Apply for W81XWH 22 LRP IA Funding Number: W81XWH 22 LRP IA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Lupus, Transformative Vision Award Apply for W81XWH 22 LRP TVA Funding Number: W81XWH 22 LRP TVA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DoD Military Burn, Clinical Translational Research Award Apply for W81XWH 22 MBRP CTRA Funding Number: W81XWH 22 MBRP CTRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Military Burn, Technology/Therapeutic Development Award Apply for W81XWH 22 MBRP TTDA Funding Number: W81XWH 22 MBRP TTDA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DOD Chronic Pain Management, Investigator-Initiated Research Award Apply for W81XWH 22 CPMRP IIRA Funding Number: W81XWH 22 CPMRP IIRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DOD Chronic Pain Management, Translational Research Award Apply for W81XWH 22 CPMRP TRA Funding Number: W81XWH 22 CPMRP TRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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