Opportunity Information: Apply for W81XWH 19 SCIRP CTA
The Department of Defense Spinal Cord Injury Research Program (SCIRP) Clinical Trial Award (CTA), funding opportunity number W81XWH 19 SCIRP CTA, is a discretionary research and development grant/cooperative agreement mechanism run through the Department of Defense, Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA). Its core purpose is to accelerate the launch and execution of clinical trials in spinal cord injury (SCI) that could meaningfully change how SCI is treated or managed in real-world clinical settings. The emphasis is on speed to implementation and on trials that are positioned to produce clinically relevant evidence, rather than early exploratory laboratory work.
The opportunity is designed to support a broad range of SCI-focused clinical studies, including trials that test promising new products and interventions such as pharmacologic agents (both drugs and biologics), medical devices, clinical guidance or care approaches, and emerging technologies. In practice, this means applicants can propose studies that evaluate novel therapeutics, rehabilitation strategies, neuromodulation or assistive technologies, diagnostic or monitoring tools, or other interventions intended to improve outcomes for individuals living with SCI. The program framing makes it clear that the funder is looking for work with a plausible path to changing patient care, whether through improved function, reduced complications, better symptom control, or more effective clinical decision-making.
A notable feature of this CTA is the wide span of allowable trial maturity. Projects can be smaller, early-stage proof-of-concept efforts, including pilot studies, first-in-human work, or Phase 0 trials, when the goal is to show feasibility, demonstrate safety signals, refine protocols, or generate the data needed to justify and properly design a larger pivotal study. At the same time, the mechanism can support larger-scale trials aimed at determining efficacy in appropriate patient populations, suggesting the program is open to well-developed trials that are ready to answer definitive clinical questions. This flexibility allows investigators and institutions to align their proposal with the current readiness of their intervention while still fitting within a clinical trial framework.
Eligibility is listed as unrestricted, meaning the competition is broadly open to any type of applicant organization, subject to any additional clarifications that may be provided in the full announcement. The funding activity category is Science and Technology and other Research and Development, with CFDA number 12.420. The funding instruments available are grants and cooperative agreements, which generally indicates that some awards may involve a closer working relationship with the government compared with a standard grant, depending on the project and award structure.
Administratively, the opportunity was created on April 15, 2019, with an original closing date of August 27, 2019, and it anticipated making about three awards. The published award ceiling is listed as 0, which typically signals that a maximum dollar amount was not stated in the summary field and would need to be confirmed in the full funding announcement and associated program guidelines. Overall, the CTA is positioned as a mechanism for moving SCI interventions into clinical testing quickly, supporting trials that range from early feasibility work to larger efficacy studies, with the overarching aim of producing evidence that can significantly improve treatment or management of spinal cord injury.Apply for W81XWH 19 SCIRP CTA
- The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Spinal Cord Injury, Clinical Trial Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on Apr 15, 2019.
- Applicants must submit their applications by Aug 27, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQs)
What is the SCIRP Clinical Trial Award (CTA)?
The Spinal Cord Injury Research Program (SCIRP) Clinical Trial Award (CTA) is a Department of Defense funding mechanism intended to accelerate the launch and execution of clinical trials focused on spinal cord injury (SCI).
Which government offices run this funding opportunity?
This opportunity is run through the Department of Defense, Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA).
What is the funding opportunity number?
The funding opportunity number is W81XWH 19 SCIRP CTA.
What is the main purpose of this award?
The core purpose is to speed up real-world, clinically relevant SCI trials that could meaningfully change how spinal cord injury is treated or managed in clinical settings.
Is the focus more on basic research or clinical evidence generation?
The emphasis is on speed to implementation and producing clinically relevant evidence. It is positioned for clinical trial execution rather than early exploratory laboratory work.
What kinds of studies are supported under this opportunity?
The CTA is designed to support a broad range of SCI-focused clinical studies, including trials of promising new products and interventions intended to improve outcomes for people living with SCI.
What types of interventions can be tested in these clinical trials?
Examples described include pharmacologic agents (drugs and biologics), medical devices, clinical guidance or care approaches, and emerging technologies. Applicants may propose studies evaluating therapeutics, rehabilitation strategies, neuromodulation or assistive technologies, diagnostic or monitoring tools, or other SCI interventions.
What kinds of patient or clinical benefits is the program trying to support?
The program framing highlights interventions with a plausible path to changing patient care, including improved function, reduced complications, better symptom control, or more effective clinical decision-making.
Does the program allow early-stage clinical trials?
Yes. The CTA allows smaller, early-stage proof-of-concept efforts, including pilot studies, first-in-human work, or Phase 0 trials, when the purpose is feasibility, safety signals, protocol refinement, or generating data to justify and design a larger pivotal study.
Does the program also allow larger, later-stage efficacy trials?
Yes. The mechanism can support larger-scale trials aimed at determining efficacy in appropriate patient populations, indicating it is open to well-developed trials ready to answer definitive clinical questions.
How flexible is this award in terms of trial maturity or readiness?
It is described as flexible across a wide span of trial maturity, allowing investigators to align proposals with the readiness level of their intervention while still operating within a clinical trial framework.
Who is eligible to apply?
Eligibility is listed as unrestricted, meaning it is broadly open to any type of applicant organization, subject to any additional clarifications that may appear in the full announcement.
What type of funding mechanism is this (grant, contract, or something else)?
This is a discretionary research and development grant/cooperative agreement mechanism. The available funding instruments are grants and cooperative agreements.
What does it mean that both grants and cooperative agreements are available?
It indicates that some awards may be issued as cooperative agreements, which generally can involve a closer working relationship with the government than a standard grant, depending on the project and award structure.
What is the funding activity category for this opportunity?
The funding activity category is listed as Science and Technology and other Research and Development.
What is the CFDA number associated with this opportunity?
The CFDA number is 12.420.
When was this opportunity created?
The opportunity was created on April 15, 2019.
What was the original closing date?
The original closing date was August 27, 2019.
How many awards were anticipated?
The opportunity anticipated making about three awards.
What is the maximum award amount (award ceiling)?
The published award ceiling is listed as 0 in the summary, which typically means a maximum dollar amount was not stated in that summary field and would need to be confirmed in the full funding announcement and associated program guidelines.
What is the overall goal of the program in practical terms?
Overall, the CTA is positioned to move SCI interventions into clinical testing quickly, supporting trials from early feasibility through larger efficacy studies, with the overarching aim of generating evidence that can significantly improve treatment or management of spinal cord injury.
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| Funding Opportunity |
|---|
| DoD Spinal Cord Injury, Investigator- Initiated Research Award Apply for W81XWH 19 SCIRP IIRA Funding Number: W81XWH 19 SCIRP IIRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Spinal Cord Injury, Translational Research Award Apply for W81XWH 19 SCIRP TRA Funding Number: W81XWH 19 SCIRP TRA Agency: Department of Defense, Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Cooperative Ecosystem Studies Unit, Rocky Mountain CESU Apply for G19AS00048 Funding Number: G19AS00048 Agency: Department of the Interior, U. S. Geological Survey Category: Science and Technology and other Research and Development Funding Amount: $48,801 |
| Cooperative Ecosystem Studies Unit, Colorado Plateau CESU Apply for G19AS00049 Funding Number: G19AS00049 Agency: Department of the Interior, U. S. Geological Survey Category: Science and Technology and other Research and Development Funding Amount: $115,768 |
| Cooperative Ecosystem Studies Unit, North and West Alaska CESU Apply for G19AS00047 Funding Number: G19AS00047 Agency: Department of the Interior, U. S. Geological Survey Category: Science and Technology and other Research and Development Funding Amount: $80,364 |
| Scientific Machine Learning and Artificial Intelligence: Uncertainty Quantification Apply for DE FOA 0002122 Funding Number: DE FOA 0002122 Agency: Department of Energy - Office of Science, Office of Science Category: Science and Technology and other Research and Development Funding Amount: $150,000 |
| Dark Matter New Initiatives Apply for DE FOA 0002112 Funding Number: DE FOA 0002112 Agency: Department of Energy - Office of Science, Office of Science Category: Science and Technology and other Research and Development Funding Amount: $3,000,000 |
| Disability and Rehabilitation Research Projects (DRRP): Assistive Technology to Promote Independence and Community Living (Research) Apply for HHS 2019 ACL NIDILRR DPGE 0354 Funding Number: HHS 2019 ACL NIDILRR DPGE 0354 Agency: Department of Health and Human Services, Administration for Community Living Category: Science and Technology and other Research and Development Funding Amount: $1,333,332 |
| Disability and Rehabilitation Research Projects (DRRP): Assistive Technology to Promote Independence and Community Living (Development) Apply for HHS 2019 ACL NIDILRR DPGE 0355 Funding Number: HHS 2019 ACL NIDILRR DPGE 0355 Agency: Department of Health and Human Services, Administration for Community Living Category: Science and Technology and other Research and Development Funding Amount: $1,333,332 |
| Fiscal Year (FY) 2019 Cooperating Technical Partners (CTP) Program - Region 3 Apply for DHS 19 MT 045 03 01 Funding Number: DHS 19 MT 045 03 01 Agency: Department of Homeland Security, Department of Homeland Security - FEMA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Fiscal Year (FY) 2019 Cooperating Technical Partners (CTP) Program - Region 4 Apply for DHS 19 MT 045 04 01 Funding Number: DHS 19 MT 045 04 01 Agency: Department of Homeland Security, Department of Homeland Security - FEMA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Fiscal Year (FY) 2019 Cooperating Technical Partners (CTP) Program - Region 7 Apply for DHS 19 MT 045 07 01 Funding Number: DHS 19 MT 045 07 01 Agency: Department of Homeland Security, Department of Homeland Security - FEMA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Fiscal Year (FY) 2019 Cooperating Technical Partners (CTP) Program - Region 8 Apply for DHS 19 MT 045 08 01 Funding Number: DHS 19 MT 045 08 01 Agency: Department of Homeland Security, Department of Homeland Security - FEMA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Fiscal Year (FY) 2019 Cooperating Technical Partners (CTP) Program - Region 10 Apply for DHS 19 MT 045 10 01 Funding Number: DHS 19 MT 045 10 01 Agency: Department of Homeland Security, Department of Homeland Security - FEMA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Nuclear Data Interagency Working Group / Research Program Apply for DE FOA 0002114 Funding Number: DE FOA 0002114 Agency: Department of Energy - Office of Science, Office of Science Category: Science and Technology and other Research and Development Funding Amount: $2,000,000 |
| Fiscal Year (FY) 2019 Cooperating Technical Partners (CTP) Program - Region 9 Apply for DHS 19 MT 045 09 01 Funding Number: DHS 19 MT 045 09 01 Agency: Department of Homeland Security, Department of Homeland Security - FEMA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Fiscal Year (FY) 2019 Cooperating Technical Partners (CTP) Program - HQ Apply for DHS 19 MT 045 00 01 Funding Number: DHS 19 MT 045 00 01 Agency: Department of Homeland Security, Department of Homeland Security - FEMA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Fiscal Year (FY) 2019 Cooperating Technical Partners (CTP) Program - Region 2 Apply for DHS 19 MT 045 02 01 Funding Number: DHS 19 MT 045 02 01 Agency: Department of Homeland Security, Department of Homeland Security - FEMA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Fiscal Year (FY) 2019 Cooperating Technical Partners (CTP) Program - Region 5 Apply for DHS 19 MT 045 05 01 Funding Number: DHS 19 MT 045 05 01 Agency: Department of Homeland Security, Department of Homeland Security - FEMA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Fiscal Year (FY) 2019 Cooperating Technical Partners (CTP) Program - Region 6 Apply for DHS 19 MT 045 06 01 Funding Number: DHS 19 MT 045 06 01 Agency: Department of Homeland Security, Department of Homeland Security - FEMA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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